Llwytho...

Early blockade of joint inflammation with a fatty acid amide hydrolase inhibitor decreases end-stage osteoarthritis pain and peripheral neuropathy in mice

BACKGROUND: The endocannabinoid system has been shown to reduce inflammatory flares and pain in rodent models of arthritis. A limitation of endocannabinoids is that they are rapidly denatured by hydrolysing enzymes such as fatty acid amide hydrolase (FAAH) which renders them physiologically inert. O...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Arthritis Res Ther
Prif Awduron: McDougall, Jason J., Muley, Milind M., Philpott, Holly T., Reid, Allison, Krustev, Eugene
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5445456/
https://ncbi.nlm.nih.gov/pubmed/28545594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-017-1313-1
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