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The unique C- and N-terminal sequences of Metallothionein isoform 3 mediate growth inhibition and Vectorial active transport in MCF-7 cells

BACKGROUND: The 3rd isoform of the metallothionein (MT3) gene family has been shown to be overexpressed in most ductal breast cancers. A previous study has shown that the stable transfection of MCF-7 cells with the MT3 gene inhibits cell growth. The goal of the present study was to determine the rol...

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Publicat a:BMC Cancer
Autors principals: Voels, Brent, Wang, Liping, Sens, Donald A., Garrett, Scott H., Zhang, Ke, Somji, Seema
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5445401/
https://ncbi.nlm.nih.gov/pubmed/28545470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3355-9
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