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Protein interactions with metallothionein-3 promote vectorial active transport in human proximal tubular cells.

Metallothionein 3 (MT-3) is a small, cysteine-rich protein that binds to essential metals required for homeostasis, as well as to heavy metals that have the potential to exert toxic effects on cells. MT-3 is expressed by epithelial cells of the human kidney, including the cells of the proximal tubul...

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Detalhes bibliográficos
Main Authors: Gazal Kalyan, Andrea Slusser-Nore, Jane R Dunlevy, Chandra S Bathula, John B Shabb, Wallace Muhonen, Seema Somji, Donald A Sens, Scott H Garrett
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2022-01-01
Colecção:PLoS ONE
Acesso em linha:https://doi.org/10.1371/journal.pone.0267599
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