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Quantitation of Human Metallothionein Isoforms: A Family of Small, Highly Conserved, Cysteine-rich Proteins

Human metallothioneins (MTs) are important regulators of metal homeostasis and protectors against oxidative damage. Their altered mRNA expression has been correlated with metal toxicity and a variety of cancers. Current immunodetection methods lack the specificity to distinguish all 12 human isoform...

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Библиографические подробности
Главные авторы: Mehus, Aaron A., Muhonen, Wallace W., Garrett, Scott H., Somji, Seema, Sens, Donald A., Shabb, John B.
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Biochemistry and Molecular Biology 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977181/
https://ncbi.nlm.nih.gov/pubmed/24493013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M113.033373
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