Quantitation of Human Metallothionein Isoforms: A Family of Small, Highly Conserved, Cysteine-rich Proteins

Human metallothioneins (MTs) are important regulators of metal homeostasis and protectors against oxidative damage. Their altered mRNA expression has been correlated with metal toxicity and a variety of cancers. Current immunodetection methods lack the specificity to distinguish all 12 human isoform...

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Detalhes bibliográficos
Main Authors: Mehus, Aaron A., Muhonen, Wallace W., Garrett, Scott H., Somji, Seema, Sens, Donald A., Shabb, John B.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977181/
https://ncbi.nlm.nih.gov/pubmed/24493013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M113.033373
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