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A computational assessment of pH-dependent differential interaction of T7 lysozyme with T7 RNA polymerase

BACKGROUND: T7 lysozyme (T7L), also known as N-acetylmuramoyl-L-alanine amidase, is a T7 bacteriophage gene product. It involves two functions: It can cut amide bonds in the bacterial cell wall and interacts with T7 RNA polymerase (T7RNAP) as a part of transcription inhibition. In this study, with t...

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Vydáno v:BMC Struct Biol
Hlavní autoři: Borkotoky, Subhomoi, Murali, Ayaluru
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5445346/
https://ncbi.nlm.nih.gov/pubmed/28545576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12900-017-0077-9
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