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A sensitive mass spectrometry platform identifies metabolic changes of life history traits in C. elegans

Abnormal nutrient metabolism is a hallmark of aging, and the underlying genetic and nutritional framework is rapidly being uncovered, particularly using C. elegans as a model. However, the direct metabolic consequences of perturbations in life history of C. elegans remain to be clarified. Based on r...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Gao, Arwen W., Chatzispyrou, Iliana A., Kamble, Rashmi, Liu, Yasmine J., Herzog, Katharina, Smith, Reuben L., van Lenthe, Henk, Vervaart, Martin A. T., van Cruchten, Arno, Luyf, Angela C., van Kampen, Antoine, Pras-Raves, Mia L., Vaz, Frédéric M., Houtkooper, Riekelt H.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5445081/
https://ncbi.nlm.nih.gov/pubmed/28546536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02539-w
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