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A sensitive mass spectrometry platform identifies metabolic changes of life history traits in C. elegans

Abnormal nutrient metabolism is a hallmark of aging, and the underlying genetic and nutritional framework is rapidly being uncovered, particularly using C. elegans as a model. However, the direct metabolic consequences of perturbations in life history of C. elegans remain to be clarified. Based on r...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gao, Arwen W., Chatzispyrou, Iliana A., Kamble, Rashmi, Liu, Yasmine J., Herzog, Katharina, Smith, Reuben L., van Lenthe, Henk, Vervaart, Martin A. T., van Cruchten, Arno, Luyf, Angela C., van Kampen, Antoine, Pras-Raves, Mia L., Vaz, Frédéric M., Houtkooper, Riekelt H.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5445081/
https://ncbi.nlm.nih.gov/pubmed/28546536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02539-w
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