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Structure-based assessment of disease-related mutations in human voltage-gated sodium channels

Voltage-gated sodium (Na(v)) channels are essential for the rapid upstroke of action potentials and the propagation of electrical signals in nerves and muscles. Defects of Na(v) channels are associated with a variety of channelopathies. More than 1000 disease-related mutations have been identified i...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Protein Cell
Prif Awduron: Huang, Weiyun, Liu, Minhao, Yan, S. Frank, Yan, Nieng
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Higher Education Press 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5445024/
https://ncbi.nlm.nih.gov/pubmed/28150151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-017-0372-z
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