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Breg dependent islet transplant tolerance is also NK-cell dependent

Immunologic tolerance to solid organ and islet cell grafts has been achieved in various rodent models using antibodies directed at CD45RB and Tim-1. We have shown that this form of tolerance depends on regulatory B-cells. To elucidate further the mechanism by which Bregs induce tolerance we investig...

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Detalhes bibliográficos
Publicado no:Am J Transplant
Main Authors: Schuetz, Christian, Lee, Kang Mi, Scott, Ryan, Kojima, Lisa, Washburn, Laura, Liu, Liye, Liu, Wei-Hui, Tector, Haley, Lei, Ji, Yeh, Heidi, Kim, James, Markmann, James F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5444975/
https://ncbi.nlm.nih.gov/pubmed/28296255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.14265
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