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The current status and future directions of hepatitis B antiviral drug discovery
INTRODUCTION: The current standard care of chronic hepatitis B fails to induce a durable off-drug control of HBV replication in the vast majority of treated patients. The primary reasons are its inability to eliminate the covalently closed circular (ccc) DNA, the nuclear form of HBV genome, and rest...
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| Publicado no: | Expert Opin Drug Discov |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5444906/ https://ncbi.nlm.nih.gov/pubmed/27797587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/17460441.2017.1255195 |
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