Rapamycin promotes differentiation increasing βIII-tubulin, NeuN, and NeuroD while suppressing nestin expression in glioblastoma cells

Glioblastoma cells feature mammalian target of rapamycin (mTOR) up-regulation which relates to a variety of effects such as: lower survival, higher infiltration, high stemness and radio- and chemo-resistance. Recently, it was demonstrated that mTOR may produce a gene shift leading to altered protein...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Ferrucci, Michela, Biagioni, Francesca, Lenzi, Paola, Gambardella, Stefano, Ferese, Rosangela, Calierno, Maria Teresa, Falleni, Alessandra, Grimaldi, Alfonso, Frati, Alessandro, Esposito, Vincenzo, Limatola, Cristina, Fornai, Francesco
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Research Paper: Gerotarget (Focus on Aging)
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5444688/
https://ncbi.nlm.nih.gov/pubmed/28418837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15906
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars