Targeted Delivery of FLT-Morpholino Using Cyclic RGD Peptide

PURPOSE: We previously showed that intravitreal injection of the sFLT morpholino-oligomer (FLT-MO) suppresses laser-induced choroidal neovascularization (CNV) in mice by decreasing the membrane bound form of Flt-1 while increasing the soluble form of Flt-1 via alternative splicing shift. In this stu...

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Gepubliceerd in:Transl Vis Sci Technol
Hoofdauteurs: Uehara, Hironori, Muddana, Santosh Kumar, Zhang, Xiaohui, Das, Subrata Kumar, Bhuvanagiri, Sai, Liu, Jinlu, Wu, Yuanyuan, Choi, Susie, Carroll, Lara S., Archer, Bonnie, Ambati, Balamurali K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Association for Research in Vision and Ophthalmology 2017
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Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5444505/
https://ncbi.nlm.nih.gov/pubmed/28553563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/tvst.6.3.9
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