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Vascular Endothelial Growth Factor Receptor 1 Morpholino Decreases Angiogenesis in a Murine Corneal Suture Model
PURPOSE. This study sought to determine whether a vascular endothelial growth factor receptor 1 (VEGFR1)–specific morpholino could induce the alternative splicing of Flt-1 pre-mRNA to downregulate membrane-bound Flt-1 (mFlt-1) and increase the production of soluble Flt-1 (sFlt-1), thereby limiting a...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Association for Research in Vision and Ophthalmology, Inc.
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3317414/ https://ncbi.nlm.nih.gov/pubmed/22199251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-8391 |
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