Pharmacokinetics and Tolerance of the Phage Endolysin-Based Candidate Drug SAL200 after a Single Intravenous Administration among Healthy Volunteers

This study was a phase 1, single-center, randomized, double-blind, placebo-controlled, single-dosing, and dose-escalating study of intravenous SAL200. It is a new candidate drug for the treatment of antibiotic-resistant staphylococcal infections based on a recombinant form of the phage endolysin SAL...

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Detaylı Bibliyografya
Yayımlandı:Antimicrob Agents Chemother
Asıl Yazarlar: Jun, Soo Youn, Jang, In Jin, Yoon, Seonghae, Jang, Kyungho, Yu, Kyung-Sang, Cho, Joo Youn, Seong, Moon-Woo, Jung, Gi Mo, Yoon, Seong Jun, Kang, Sang Hyeon
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2017
Konular:
Clinical Therapeutics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5444177/
https://ncbi.nlm.nih.gov/pubmed/28348152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02629-16
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