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Preclinical Safety Evaluation of Intravenously Administered SAL200 Containing the Recombinant Phage Endolysin SAL-1 as a Pharmaceutical Ingredient

Phage endolysins have received increasing attention as potent antibacterial agents. However, although safety evaluation is a prerequisite for the drug development process, a good laboratory practice (GLP)-compliant safety evaluation has not been reported for phage endolysins. A safety evaluation of...

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Detalhes bibliográficos
Main Authors: Jun, Soo Youn, Jung, Gi Mo, Yoon, Seong Jun, Choi, Yun-Jaie, Koh, Woo Suk, Moon, Kyoung Sik, Kang, Sang Hyeon
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023757/
https://ncbi.nlm.nih.gov/pubmed/24449776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02232-13
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