Type 2 diabetes and obesity induce similar transcriptional reprogramming in human myocytes

BACKGROUND: Skeletal muscle is one of the primary tissues involved in the development of type 2 diabetes (T2D). The close association between obesity and T2D makes it difficult to isolate specific effects attributed to the disease alone. Therefore, here we set out to identify and characterize intrin...

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Detalhes bibliográficos
Publicado no:Genome Med
Main Authors: Väremo, Leif, Henriksen, Tora Ida, Scheele, Camilla, Broholm, Christa, Pedersen, Maria, Uhlén, Mathias, Pedersen, Bente Klarlund, Nielsen, Jens
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5444103/
https://ncbi.nlm.nih.gov/pubmed/28545587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-017-0432-2
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