Type 2 diabetes and obesity induce similar transcriptional reprogramming in human myocytes

BACKGROUND: Skeletal muscle is one of the primary tissues involved in the development of type 2 diabetes (T2D). The close association between obesity and T2D makes it difficult to isolate specific effects attributed to the disease alone. Therefore, here we set out to identify and characterize intrin...

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Publicado en:Genome Med
Autores principales: Väremo, Leif, Henriksen, Tora Ida, Scheele, Camilla, Broholm, Christa, Pedersen, Maria, Uhlén, Mathias, Pedersen, Bente Klarlund, Nielsen, Jens
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5444103/
https://ncbi.nlm.nih.gov/pubmed/28545587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-017-0432-2
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