Expression and functional assessment of candidate type 2 diabetes susceptibility genes identify four new genes contributing to human insulin secretion

OBJECTIVES: Genome-wide association studies (GWAS) have identified >100 loci independently contributing to type 2 diabetes (T2D) risk. However, translational implications for precision medicine and for the development of novel treatments have been disappointing, due to poor knowledge of how these...

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Bibliografiska uppgifter
I publikationen:Mol Metab
Huvudupphovsmän: Ndiaye, Fatou K., Ortalli, Ana, Canouil, Mickaël, Huyvaert, Marlène, Salazar-Cardozo, Clara, Lecoeur, Cécile, Verbanck, Marie, Pawlowski, Valérie, Boutry, Raphaël, Durand, Emmanuelle, Rabearivelo, Iandry, Sand, Olivier, Marselli, Lorella, Kerr-Conte, Julie, Chandra, Vikash, Scharfmann, Raphaël, Poulain-Godefroy, Odile, Marchetti, Piero, Pattou, François, Abderrahmani, Amar, Froguel, Philippe, Bonnefond, Amélie
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2017
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Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5444093/
https://ncbi.nlm.nih.gov/pubmed/28580277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2017.03.011
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