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Protein Kinase C Epsilon Cooperates with Pten Loss for Prostate Tumorigenesis Through the Cxcl13-Cxcr5 Pathway

PKCε, an oncogenic member of the PKC family, is aberrantly overexpressed in epithelial cancers. To date, little is known about functional interactions of PKCε with other genetic alterations as well as the effectors contributing to its tumorigenic and metastatic phenotype. Here, we demonstrate that P...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Garg, Rachana, Blando, Jorge M., Perez, Carlos J., Abba, Martin C., Benavides, Fernando, Kazanietz, Marcelo G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5444089/
https://ncbi.nlm.nih.gov/pubmed/28402859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.03.042
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