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Robustness analysis of the detailed kinetic model of an ErbB signaling network by using dynamic sensitivity

The ErbB receptor signaling pathway plays an important role in the regulation of cellular proliferation, survival and differentiation, and dysregulation of the pathway is linked to various types of human cancer. Mathematical models have been developed as a practical complementary approach to deciphe...

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Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Masunaga, Hiroyuki, Sugimoto, Yurie, Magi, Shigeyuki, Itasaki, Ryunosuke, Okada-Hatakeyama, Mariko, Kurata, Hiroyuki
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5443533/
https://ncbi.nlm.nih.gov/pubmed/28542548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178250
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