Genetic deletion of the Nogo receptor does not reduce neurite inhibition in vitro or promote corticospinal tract regeneration in vivo

Axon regeneration failure in the adult mammalian CNS is attributed in part to the inhibitory nature of CNS myelin. Three myelin-associated, structurally distinct proteins, Nogo, myelin-associated glycoprotein, and oligodendrocyte myelin glycoprotein, have been implicated in this inhibition. Neuronal...

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Bibliographic Details
Main Authors: Zheng, Binhai, Atwal, Jasvinder, Ho, Carole, Case, Lauren, He, Xiao-lin, Garcia, K. Christopher, Steward, Oswald, Tessier-Lavigne, Marc
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2005
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC544342/
https://ncbi.nlm.nih.gov/pubmed/15647357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409026102
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