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Genetic deletion of the Nogo receptor does not reduce neurite inhibition in vitro or promote corticospinal tract regeneration in vivo

Axon regeneration failure in the adult mammalian CNS is attributed in part to the inhibitory nature of CNS myelin. Three myelin-associated, structurally distinct proteins, Nogo, myelin-associated glycoprotein, and oligodendrocyte myelin glycoprotein, have been implicated in this inhibition. Neuronal...

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Autors principals: Zheng, Binhai, Atwal, Jasvinder, Ho, Carole, Case, Lauren, He, Xiao-lin, Garcia, K. Christopher, Steward, Oswald, Tessier-Lavigne, Marc
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC544342/
https://ncbi.nlm.nih.gov/pubmed/15647357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409026102
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