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Genetic deletion of the Nogo receptor does not reduce neurite inhibition in vitro or promote corticospinal tract regeneration in vivo

Axon regeneration failure in the adult mammalian CNS is attributed in part to the inhibitory nature of CNS myelin. Three myelin-associated, structurally distinct proteins, Nogo, myelin-associated glycoprotein, and oligodendrocyte myelin glycoprotein, have been implicated in this inhibition. Neuronal...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zheng, Binhai, Atwal, Jasvinder, Ho, Carole, Case, Lauren, He, Xiao-lin, Garcia, K. Christopher, Steward, Oswald, Tessier-Lavigne, Marc
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC544342/
https://ncbi.nlm.nih.gov/pubmed/15647357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409026102
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