Virus-like particle vaccines containing F or F and G proteins confer protection against respiratory syncytial virus without pulmonary inflammation in cotton rats

Vaccine-enhanced disease has been a major obstacle in developing a safe vaccine against respiratory syncytial virus (RSV). This study demonstrates the immunogenicity, efficacy, and safety of virus-like particle (VLP) vaccines containing RSV F (F VLP), G (G VLP), or F and G proteins (FG VLP) in cotto...

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Detalles Bibliográficos
Publicado en:Hum Vaccin Immunother
Main Authors: Hwang, Hye Suk, Kim, Ki-Hye, Lee, Youri, Lee, Young-Tae, Ko, Eun-Ju, Park, SooJin, Lee, Jong Seok, Lee, Byung-cheol, Kwon, Young-Man, Moore, Martin L., Kang, Sang-Moo
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2017
Assuntos:
Research Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5443399/
https://ncbi.nlm.nih.gov/pubmed/28129031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2016.1272743
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