Generation of Human Induced Pluripotent Stem Cell‐Derived Bona Fide Neural Stem Cells for Ex Vivo Gene Therapy of Metachromatic Leukodystrophy

Allogeneic fetal‐derived human neural stem cells (hfNSCs) that are under clinical evaluation for several neurodegenerative diseases display a favorable safety profile, but require immunosuppression upon transplantation in patients. Neural progenitors derived from patient‐specific induced pluripotent...

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Detalhes bibliográficos
Publicado no:Stem Cells Transl Med
Main Authors: Meneghini, Vasco, Frati, Giacomo, Sala, Davide, De Cicco, Silvia, Luciani, Marco, Cavazzin, Chiara, Paulis, Marianna, Mentzen, Wieslawa, Morena, Francesco, Giannelli, Serena, Sanvito, Francesca, Villa, Anna, Bulfone, Alessandro, Broccoli, Vania, Martino, Sabata, Gritti, Angela
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Translational Research Articles and Reviews
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5442804/
https://ncbi.nlm.nih.gov/pubmed/28191778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2015-0414
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