Generation of Human Induced Pluripotent Stem Cell‐Derived Bona Fide Neural Stem Cells for Ex Vivo Gene Therapy of Metachromatic Leukodystrophy

Allogeneic fetal‐derived human neural stem cells (hfNSCs) that are under clinical evaluation for several neurodegenerative diseases display a favorable safety profile, but require immunosuppression upon transplantation in patients. Neural progenitors derived from patient‐specific induced pluripotent...

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Bibliografiske detaljer
Udgivet i:Stem Cells Transl Med
Main Authors: Meneghini, Vasco, Frati, Giacomo, Sala, Davide, De Cicco, Silvia, Luciani, Marco, Cavazzin, Chiara, Paulis, Marianna, Mentzen, Wieslawa, Morena, Francesco, Giannelli, Serena, Sanvito, Francesca, Villa, Anna, Bulfone, Alessandro, Broccoli, Vania, Martino, Sabata, Gritti, Angela
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Translational Research Articles and Reviews
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5442804/
https://ncbi.nlm.nih.gov/pubmed/28191778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2015-0414
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