Safety and Efficacy of Megakaryocytes Induced from Hematopoietic Stem Cells in Murine and Nonhuman Primate Models

Because of a lack of platelet supply and a U.S. Food and Drug Administration‐approved platelet growth factor, megakaryocytes have emerged as an effective substitute for alleviating thrombocytopenia. Here, we report the development of an efficient two‐stage culture system that is free of stroma, anim...

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Bibliografiska uppgifter
I publikationen:Stem Cells Transl Med
Huvudupphovsmän: Guan, Xin, Qin, Meng, Zhang, Yu, Wang, Yanan, Shen, Bin, Ren, Zhihua, Ding, Xinxin, Dai, Wei, Jiang, Yongping
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2016
Ämnen:
Translational Research Articles and Reviews
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5442772/
https://ncbi.nlm.nih.gov/pubmed/28297572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2016-0224
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