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Safety and Efficacy of Megakaryocytes Induced from Hematopoietic Stem Cells in Murine and Nonhuman Primate Models

Because of a lack of platelet supply and a U.S. Food and Drug Administration‐approved platelet growth factor, megakaryocytes have emerged as an effective substitute for alleviating thrombocytopenia. Here, we report the development of an efficient two‐stage culture system that is free of stroma, anim...

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Detalhes bibliográficos
Publicado no:Stem Cells Transl Med
Main Authors: Guan, Xin, Qin, Meng, Zhang, Yu, Wang, Yanan, Shen, Bin, Ren, Zhihua, Ding, Xinxin, Dai, Wei, Jiang, Yongping
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5442772/
https://ncbi.nlm.nih.gov/pubmed/28297572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2016-0224
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