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Protective Role for Macrophages in Respiratory Francisella tularensis Infection

Francisella tularensis causes lethal pneumonia following infection of the lungs by targeting macrophages for intracellular replication; however, macrophages stimulated with interferon gamma (IFN-γ) can resist infection in vitro. We therefore hypothesized that the protective effect of IFN-γ against F...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Steiner, Donald J., Furuya, Yoichi, Jordan, Michael B., Metzger, Dennis W.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5442621/
https://ncbi.nlm.nih.gov/pubmed/28373354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00064-17
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