Increased Tuberculosis Patient Mortality Associated with Mycobacterium tuberculosis Mutations Conferring Resistance to Second-Line Antituberculous Drugs

Rapid molecular diagnostics have great potential to limit the spread of multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB) (M/XDR-TB). These technologies detect mutations in the Mycobacterium tuberculosis genome that confer phenotypic drug resistance. Howe...

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Bibliographic Details
Published in:J Clin Microbiol
Main Authors: Georghiou, Sophia B., Seifert, Marva, Catanzaro, Donald G., Garfein, Richard S., Rodwell, Timothy C.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2017
Subjects:
Mycobacteriology and Aerobic Actinomycetes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5442550/
https://ncbi.nlm.nih.gov/pubmed/28404672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00152-17
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