MTBDRplus and MTBDRsl Assays: Absence of Wild-Type Probe Hybridization and Implications for Detection of Drug-Resistant Tuberculosis

Accurate identification of drug-resistant Mycobacterium tuberculosis is imperative for effective treatment and subsequent reduction in disease transmission. Line probe assays rapidly detect mutations associated with resistance and wild-type sequences associated with susceptibility. Examination of mo...

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Bibliographic Details
Published in:J Clin Microbiol
Main Authors: Seifert, Marva, Georghiou, Sophia B., Catanzaro, Donald, Rodrigues, Camilla, Crudu, Valeriu, Victor, Thomas C., Garfein, Richard S., Catanzaro, Antonino, Rodwell, Timothy C.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
Subjects:
Mycobacteriology and Aerobic Actinomycetes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4809938/
https://ncbi.nlm.nih.gov/pubmed/26763971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.02505-15
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