Hundreds of dual-stage antimalarial molecules discovered by a functional gametocyte screen

Plasmodium falciparum stage V gametocytes are responsible for parasite transmission, and drugs targeting this stage are needed to support malaria elimination. We here screen the Tres Cantos Antimalarial Set (TCAMS) using the previously developed P. falciparum female gametocyte activation assay (Pf F...

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Dettagli Bibliografici
Pubblicato in:Nat Commun
Autori principali: Miguel-Blanco, Celia, Molina, Irene, Bardera, Ana I., Díaz, Beatriz, de las Heras, Laura, Lozano, Sonia, González, Carolina, Rodrigues, Janneth, Delves, Michael J., Ruecker, Andrea, Colmenarejo, Gonzalo, Viera, Sara, Martínez-Martínez, María S., Fernández, Esther, Baum, Jake, Sinden, Robert E., Herreros, Esperanza
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5442318/
https://ncbi.nlm.nih.gov/pubmed/28513586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15160
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