Hundreds of dual-stage antimalarial molecules discovered by a functional gametocyte screen

Plasmodium falciparum stage V gametocytes are responsible for parasite transmission, and drugs targeting this stage are needed to support malaria elimination. We here screen the Tres Cantos Antimalarial Set (TCAMS) using the previously developed P. falciparum female gametocyte activation assay (Pf F...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Miguel-Blanco, Celia, Molina, Irene, Bardera, Ana I., Díaz, Beatriz, de las Heras, Laura, Lozano, Sonia, González, Carolina, Rodrigues, Janneth, Delves, Michael J., Ruecker, Andrea, Colmenarejo, Gonzalo, Viera, Sara, Martínez-Martínez, María S., Fernández, Esther, Baum, Jake, Sinden, Robert E., Herreros, Esperanza
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5442318/
https://ncbi.nlm.nih.gov/pubmed/28513586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15160
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