Epigenetic priming restores the HLA class-I antigen processing machinery expression in Merkel cell carcinoma

Merkel cell carcinoma (MCC) is a rare and aggressive, yet highly immunogenic skin cancer. The latter is due to its viral or UV-associated carcinogenesis. For tumor progression MCC has to escape the host’s immuno-surveillance, e.g. by loss of HLA class-I expression. Indeed, a reduced HLA class-I expr...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Ritter, Cathrin, Fan, Kaiji, Paschen, Annette, Reker Hardrup, Sine, Ferrone, Soldano, Nghiem, Paul, Ugurel, Selma, Schrama, David, Becker, Jürgen C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5442125/
https://ncbi.nlm.nih.gov/pubmed/28536458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02608-0
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak