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Novel insights into anti-CD40/CD154 immunotherapy in transplant tolerance
Since the discovery of the CD40-CD154 costimulatory pathway and its critical role in the adaptive immune response, there has been considerable interest in therapeutically targeting this interaction with monoclonal antibodies in transplantation. Unfortunately, initial promise in animal models gave wa...
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| Pubblicato in: | Immunotherapy |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5441999/ https://ncbi.nlm.nih.gov/pubmed/25917630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/imt.15.1 |
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