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Transient Hypothyroidism: Dual Effect on Adult-Type Leydig Cell and Sertoli Cell Development

Transient neonatal 6-propyl-2-thiouracil (PTU) induced hypothyroidism affects Leydig and Sertoli cell numbers in the developing testis, resulting in increased adult testis size. The hypothyroid condition was thought to be responsible, an assumption questioned by studies showing that uninterrupted fe...

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Bibliografski detalji
Izdano u:Front Physiol
Glavni autori: Rijntjes, Eddy, Gomes, Marcos L. M., Zupanič, Nina, Swarts, Hans J. M., Keijer, Jaap, Teerds, Katja J.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5441398/
https://ncbi.nlm.nih.gov/pubmed/28588502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00323
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