Transient Hypothyroidism: Dual Effect on Adult-Type Leydig Cell and Sertoli Cell Development

Transient neonatal 6-propyl-2-thiouracil (PTU) induced hypothyroidism affects Leydig and Sertoli cell numbers in the developing testis, resulting in increased adult testis size. The hypothyroid condition was thought to be responsible, an assumption questioned by studies showing that uninterrupted fe...

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Pubblicato in:Front Physiol
Autori principali: Rijntjes, Eddy, Gomes, Marcos L. M., Zupanič, Nina, Swarts, Hans J. M., Keijer, Jaap, Teerds, Katja J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2017
Soggetti:
Physiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5441398/
https://ncbi.nlm.nih.gov/pubmed/28588502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00323
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