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Transient Hypothyroidism: Dual Effect on Adult-Type Leydig Cell and Sertoli Cell Development

Transient neonatal 6-propyl-2-thiouracil (PTU) induced hypothyroidism affects Leydig and Sertoli cell numbers in the developing testis, resulting in increased adult testis size. The hypothyroid condition was thought to be responsible, an assumption questioned by studies showing that uninterrupted fe...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Rijntjes, Eddy, Gomes, Marcos L. M., Zupanič, Nina, Swarts, Hans J. M., Keijer, Jaap, Teerds, Katja J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5441398/
https://ncbi.nlm.nih.gov/pubmed/28588502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00323
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