VP40 Octamers Are Essential for Ebola Virus Replication

Matrix protein VP40 of Ebola virus is essential for virus assembly and budding. Monomeric VP40 can oligomerize in vitro into RNA binding octamers, and the crystal structure of octameric VP40 has revealed that residues Phe125 and Arg134 are the most important residues for the coordination of a short...

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Bibliografische gegevens
Hoofdauteurs: Hoenen, Thomas, Volchkov, Viktor, Kolesnikova, Larissa, Mittler, Eva, Timmins, Joanna, Ottmann, Michelle, Reynard, Olivier, Becker, Stephan, Weissenhorn, Winfried
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2005
Onderwerpen:
Structure and Assembly
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC544139/
https://ncbi.nlm.nih.gov/pubmed/15650213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.3.1898-1905.2005
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