Anti-CXCR4 Monoclonal Antibodies Recognizing Overlapping Epitopes Differ Significantly in Their Ability To Inhibit Entry of Human Immunodeficiency Virus Type 1

CXCR4 is one of two physiologically relevant human immunodeficiency type 1 (HIV-1) entry coreceptors. Studies of CXCR4 mutants have not clearly identified the determinants of coreceptor function and specificity. We therefore used a panel of monoclonal antibodies to further elucidate CXCR4 expression...

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Detalhes bibliográficos
Main Authors: Carnec, Xavier, Quan, Lan, Olson, William C., Hazan, Uriel, Dragic, Tatjana
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC544137/
https://ncbi.nlm.nih.gov/pubmed/15650218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.3.1930-1933.2005
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