Mutation of the SP1 Sequence Impairs both Multimerization and Membrane-Binding Activities of Human Immunodeficiency Virus Type 1 Gag

The Gag protein of human immunodeficiency virus type 1 contains a 14-amino-acid region, termed SP1, between the capsid and downstream nucleocapsid sequences. Although SP1 is known to be indispensable for virus production, the mechanisms involved are mostly unclear. In this study, we demonstrate that...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Guo, Xiaofeng, Roldan, Ariel, Hu, Jing, Wainberg, Mark A., Liang, Chen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2005
Assuntos:	Structure and Assembly
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC544129/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15650204/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.79.3.1803-1812.2005
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