Human Immunodeficiency Virus Type 1 Gag Polyprotein Multimerization Requires the Nucleocapsid Domain and RNA and Is Promoted by the Capsid-Dimer Interface and the Basic Region of Matrix Protein

The human immunodeficiency virus type 1 (HIV-1) Gag polyprotein directs the formation of virions from productively infected cells. Many gag mutations disrupt virion assembly, but little is known about the biochemical effects of many of these mutations. Protein-protein interactions among Gag monomers...

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Bibliographic Details
Main Authors: Burniston, Mark T., Cimarelli, Andrea, Colgan, John, Curtis, Sean P., Luban, Jeremy
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
Structure and Assembly
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC112873/
https://ncbi.nlm.nih.gov/pubmed/10482606
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