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An Sp1 Response Element in the Kaposi's Sarcoma-Associated Herpesvirus Open Reading Frame 50 Promoter Mediates Lytic Cycle Induction by Butyrate

Kaposi's sarcoma-associated herpesvirus (KSHV) can be driven into the lytic cycle in vitro by phorbol esters and sodium butyrate. This report begins to analyze the process by which butyrate activates the promoter of KSHV open reading frame 50 (ORF50), the key viral regulator of the KSHV latency...

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Detalhes bibliográficos
Main Authors: Ye, Jianjiang, Shedd, Duane, Miller, George
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC544116/
https://ncbi.nlm.nih.gov/pubmed/15650166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.3.1397-1408.2005
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