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Evidence for Heterogeneous Selective Pressures in the Evolution of the env Gene in Different Human Immunodeficiency Virus Type 1 Subtypes

Recent studies have demonstrated the emergence of human immunodeficiency virus type 1 (HIV-1) subtypes with various levels of fitness. Using heterogeneous maximum-likelihood models of adaptive evolution implemented in the PAML software package, with env sequences representing each HIV-1 group M subt...

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Autors principals: Travers, Simon A. A., O'Connell, Mary J., McCormack, Grace P., McInerney, James O.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC544114/
https://ncbi.nlm.nih.gov/pubmed/15650207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.3.1836-1841.2005
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