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Characterizing the emergence and persistence of drug resistant mutations in HIV-1 subtype C infections using 454 ultra deep pyrosequencing

<p>Abstract</p> <p>Background</p> <p>The role of HIV-1 RNA in the emergence of resistance to antiretroviral therapies (ARTs) is well documented while less is known about the role of historical viruses stored in the proviral DNA. The primary focus of this work was to characterize the genetic diversit...

詳細記述

保存先:
主要な著者: Bansode Vijay, McCormack Grace P, Crampin Amelia C, Ngwira Bagrey, Shrestha Ram K, French Neil, Glynn Judith R, Travers Simon A
フォーマット: Artigo
言語:Inglês
出版事項: BMC 2013-01-01
シリーズ:BMC Infectious Diseases
主題:
HIV-1
Drug resistance
Subtype C
Malawi
Ultradeep sequencing
Proviral DNA
オンライン･アクセス:http://www.biomedcentral.com/1471-2334/13/52
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