Capped RNA Transcripts of Full-Length cDNA Clones of Swine Hepatitis E Virus Are Replication Competent When Transfected into Huh7 Cells and Infectious When Intrahepatically Inoculated into Pigs

Swine hepatitis E virus (swine HEV), the first animal strain of HEV to be isolated, is a zoonotic agent. We report here the construction and in vitro and in vivo characterizations of infectious cDNA clones of swine HEV. Eight overlapping fragments spanning the entire genome were amplified by reverse...

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Hlavní autoři: Huang, Y. W., Haqshenas, G., Kasorndorkbua, C., Halbur, P. G., Emerson, S. U., Meng, X. J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2005
Témata:
Replication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC544089/
https://ncbi.nlm.nih.gov/pubmed/15650181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.3.1552-1558.2005
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