Capped RNA Transcripts of Full-Length cDNA Clones of Swine Hepatitis E Virus Are Replication Competent When Transfected into Huh7 Cells and Infectious When Intrahepatically Inoculated into Pigs

Swine hepatitis E virus (swine HEV), the first animal strain of HEV to be isolated, is a zoonotic agent. We report here the construction and in vitro and in vivo characterizations of infectious cDNA clones of swine HEV. Eight overlapping fragments spanning the entire genome were amplified by reverse...

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Detalhes bibliográficos
Main Authors: Huang, Y. W., Haqshenas, G., Kasorndorkbua, C., Halbur, P. G., Emerson, S. U., Meng, X. J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC544089/
https://ncbi.nlm.nih.gov/pubmed/15650181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.3.1552-1558.2005
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