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Gonadotoxic Effects of Nilotinib in Chronic Myeloid Leukemia Treatment Dose in a Mouse Model

OBJECTIVE: Tyrosine kinase inhibitors may have deleterious effects on spermatogenesis or folliculogenesis, resulting in male or female subfertility. The aim of this study is to determine the effect of nilotinib, which is used routinely to treat chronic myeloid leukemia, on spermatogenesis and follic...

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Bibliografiske detaljer
Udgivet i:Turk J Haematol
Main Authors: Cengiz Seval, Güldane, Özkavukçu, Sinan, Seval, Murat, Aylı, Meltem
Format: Artigo
Sprog:Inglês
Udgivet: Galenos Publishing 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5440865/
https://ncbi.nlm.nih.gov/pubmed/27466938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4274/tjh.2016.0092
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