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Gonadotoxic Effects of Nilotinib in Chronic Myeloid Leukemia Treatment Dose in a Mouse Model

OBJECTIVE: Tyrosine kinase inhibitors may have deleterious effects on spermatogenesis or folliculogenesis, resulting in male or female subfertility. The aim of this study is to determine the effect of nilotinib, which is used routinely to treat chronic myeloid leukemia, on spermatogenesis and follic...

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Podrobná bibliografie
Vydáno v:Turk J Haematol
Hlavní autoři: Cengiz Seval, Güldane, Özkavukçu, Sinan, Seval, Murat, Aylı, Meltem
Médium: Artigo
Jazyk:Inglês
Vydáno: Galenos Publishing 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5440865/
https://ncbi.nlm.nih.gov/pubmed/27466938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4274/tjh.2016.0092
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