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Critical appraisal of nilotinib in frontline treatment of chronic myeloid leukemia

The development of imatinib has revolutionized the treatment of chronic myeloid leukemia. Follow-up analysis of IRIS trial participants continues to demonstrate durable responses for imatinib at 400 mg/day. However, 10%–15% of patients with chronic myeloid leukemia will become imatinib-resistant or...

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Autori principali: DeRemer, David L, Katsanevas, Katerina, Ustun, Celalettin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085241/
https://ncbi.nlm.nih.gov/pubmed/21556318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMR.S11948
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