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Simulated rRNA/DNA Ratios Show Potential To Misclassify Active Populations as Dormant

The use of rRNA/DNA ratios derived from surveys of rRNA sequences in RNA and DNA extracts is an appealing but poorly validated approach to infer the activity status of environmental microbes. To improve the interpretation of rRNA/DNA ratios, we performed simulations to investigate the effects of com...

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Publicat a:Appl Environ Microbiol
Autors principals: Steven, Blaire, Hesse, Cedar, Soghigian, John, Gallegos-Graves, La Verne, Dunbar, John
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5440720/
https://ncbi.nlm.nih.gov/pubmed/28363969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00696-17
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