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Simulated rRNA/DNA Ratios Show Potential To Misclassify Active Populations as Dormant

The use of rRNA/DNA ratios derived from surveys of rRNA sequences in RNA and DNA extracts is an appealing but poorly validated approach to infer the activity status of environmental microbes. To improve the interpretation of rRNA/DNA ratios, we performed simulations to investigate the effects of com...

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Detalhes bibliográficos
Publicado no:Appl Environ Microbiol
Main Authors: Steven, Blaire, Hesse, Cedar, Soghigian, John, Gallegos-Graves, La Verne, Dunbar, John
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5440720/
https://ncbi.nlm.nih.gov/pubmed/28363969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00696-17
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