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Legionella effector Lpg1137 shuts down ER-mitochondria communication through cleavage of syntaxin 17
During infection of macrophages, the pathogenic bacterium Legionella pneumophila secretes effector proteins that induce the conversion of the plasma membrane-derived vacuole into an endoplasmic reticulum (ER)-like replicative vacuole. These ER-like vacuoles are ultimately fused with the ER, where th...
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| Publicat a: | Nat Commun |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5440676/ https://ncbi.nlm.nih.gov/pubmed/28504273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15406 |
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