Hyperglycemia-induced Renal P2X7 Receptor Activation Enhances Diabetes-related Injury

Diabetes is a leading cause of renal disease. Glomerular mesangial expansion and fibrosis are hallmarks of diabetic nephropathy and this is thought to be promoted by infiltration of circulating macrophages. Monocyte chemoattractant protein-1 (MCP-1) has been shown to attract macrophages in kidney di...

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Udgivet i:EBioMedicine
Main Authors: Menzies, Robert I., Booth, John W.R., Mullins, John J., Bailey, Matthew A., Tam, Frederick W.K., Norman, Jill T., Unwin, Robert J.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5440600/
https://ncbi.nlm.nih.gov/pubmed/28434946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.04.011
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