DNA Methylation Changes in Intron 1 of Triggering Receptor Expressed on Myeloid Cell 2 in Japanese Schizophrenia Subjects

A hypothesis for schizophrenia (SCZ) called the “microglia hypothesis” has been suggested. In SCZ, expression of triggering receptor expressed on myeloid cell 2 (TREM2) mRNA is higher in leukocytes than in healthy individuals. Here, the methylation rates of four CpG sites in TREM2 intron 1 that may...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Yoshino, Yuta, Ozaki, Yuki, Yamazaki, Kiyohiro, Sao, Tomoko, Mori, Yoko, Ochi, Shinichiro, Iga, Jun-ichi, Ueno, Shu-ichi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5440575/
https://ncbi.nlm.nih.gov/pubmed/28588439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2017.00275
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